Trauma and Complex Regional Pain Syndromes

A Comprehensive Guide to the Literature for Personal Injury Lawyers

Publisher: Medifocus Legal
Publication Date: February 5, 2024
Number of Pages: 96
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition characterized by disproportionate pain, sensory abnormalities and motor dysfunction. While its precise etiology remains unknown, there is growing acknowledgement of physical trauma as a significant precipitating factor in the onset and perpetuation of CRPS.

CRPS presents a multifaceted challenge in the medical-legal arena due to its intricate etiology, variable symptomology, and the complex interplay of the biological and psychosocial factors involved. Establishing causation in CRPS cases requires a comprehensive understanding of the medical evidence, legal precedent, and the unique circumstances of each individual.

In the legal realm, proving causation in CRPS cases, particularly in the context of physical trauma, requires a multidisciplinary approach that integrates medical evidence with legal analysis. Over the past few decades, a considerable amount of research has been published in peer-reviewed medical journals regarding the role of trauma in CRPS. In particular, researchers have discovered evidence elucidating the physiological changes precipitated by physical trauma that can lead to a cascade of maladaptive
changes within the peripheral and central nervous systems. This hyper-sensitization of the nervous system, in turn, can result in heightened sensitivity to pain which a hallmark feature of CRPS.

The MediFocus Literature Guide to Trauma and Complex Regional Pain Syndrome is a comprehensive guide to the medical and scientific literature that captures the body of knowledge accumulated over the past 20 years about the role of trauma in CRPS. The Guide includes numerous case reports and case series documenting the onset of CRPS in patients following a traumatic injury such as a fracture, a surgical procedure, or an injection. It also includes supporting evidence for a variety of physiological changes precipitated by trauma that can account for the abnormal sensitivity to pain in patients who suffer from CRPS. In addition, the Guide focuses on the protracted course of rehabilitation that often confronts patients with CRPS and the negative impact of this chronic pain condition on on an individual's quality of life.

Armed with the literature contained in this Guide, attorneys can present a more compelling case supported by credible medical evidence and persuasive legal arguments to achieve a more equitable resolution for their clients who developed CRPS following a traumatic injury.


Trauma and Complex Regional Pain Syndromes is a one-of-a-kind literature reference Guide that includes:

  • A comprehensive bibliography of 240 journal article references indexed in MEDLINE published in well respected medical and scientific journals.
  • Online access to the abstracts (summaries) of the articles.
  • Online access to the free full-text version of 27 articles.
  • Links to full-text sources of other articles that are available for purchase directly from individual journal publishers.
  • A unique "Author Directory" consisting of the names and institutional affiliations of experts who have published and have specialized knowledge about Trauma and Complex Regional Pain Syndromes . The "Author Directory" is a valuable resource for quickly identifying and locating experts for case reviews, opinions, and testimony.

Select examples of topics that are covered by the articles referenced in this Guidebook include:

  • Lawsuit verdicts and settlements involving reflex sympathetic dystrophy and complex regional pain syndrome.
  • Rehabilitation Interventions for Complex Regional Pain Syndrome
  • Incidence and risk factors for complex regional pain syndrome in radius fractures: meta-analysis.
  • Pain mechanisms in complex regional pain syndrome: a systematic review and meta-analysis of quantitative sensory testing outcomes.
  • Complex regional pain syndrome after mRNA-based COVID-19 vaccination.
  • Complex regional pain syndrome following vascular access creation for hemodialysis.
  • Long-term biopsychosocial issues and health-related quality of life in young adolescents and adults treated for childhood Complex Regional Pain Syndrome, type 1.
  • Complex Regional Pain Syndrome after Carpal Tunnel Syndrome Surgery: A Systematic Review.
  • Complex regional pain syndrome what is the outcome? - a systematic review of the course and impact of CRPS at 12 months from symptom onset and beyond.
  • Factors associated with disability and pain intensity in patients with complex regional pain syndrome.
  • Complex Regional Pain Syndrome and Distal Radius Fracture: Etiology, Diagnosis, and Treatment.
  • The long-term effect of complex regional pain syndrome type 1 on disability and quality of life after foot injury.
  • Complex regional pain syndrome type I following trauma
  • Health-related quality of life in 975 patients with complex regional pain syndrome type 1.
  • Complex regional pain syndrome following spine surgery: clinical and prognostic implications.
  • Complex regional pain syndrome type I as a consequence of trauma or surgery to upper extremity
  • Complex regional pain syndrome after hand surgery.
  • Complex regional pain syndrome: the role of the psychiatrist as an expert witness.
  • Systemic inflammatory mediators in post-traumatic complex regional pain syndrome
  • Post-traumatic reflex sympathetic dystrophy in the ankle and foot: a study of 32 cases.
The MediFocus Literature Guide on Trauma and Complex Regional Pain Syndromes
is available in two formats:
 
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