Adjacent Segment Disc Disease

A Comprehensive Guide to the Literature for Personal Injury Lawyers

Publisher: Medifocus Legal
Publication Date: July 5, 2016
Number of Pages: 176

The increased utilization of spinal fusion surgery in recent years has raised both awareness and concern among surgeons and patients about a complication of fusion surgery known as adjacent segment disease. This condition refers to new degenerative changes at a spinal level adjacent to a surgically treated level in the spine and is accompanied by related symptoms such as radiating pain, weakness, or spinal instability. This condition differs from adjacent segment degeneration which refers to radiographic changes of disc degeneration but without any clinical symptoms.

Although the exact cause of adjacent segment disease is currently not known, three major risk factors have been identified: 1) the natural history of normal, age-related disc degeneration; 2) increased biomechanical stress with increased motion on the next-level disc from the fusion surgery; and 3) anatomical disruption of the vertebral segment at the next-level disc resulting from the fusion.

Currently there is no gold standard treatment for adjacent segment disease and the treatment options are primarily dependent upon the severity of the clinical symptoms. Treatment can be challenging, particularly in cases with significant neurologic symptoms and instability that fail to respond to conservative treatments such as physical therapy. In this setting, revision surgery may be necessary to relieve the symptoms by decompressing the affected spinal nerve roots with possible extension of the fusion to additional levels.

The MediFocus Literature Guide to Adjacent Segment Disc Disease is a comprehensive reference guide to the medical literature for personal injury attorneys whose clients may have developed adjacent segment disease after cervical or lumbar fusion surgery. This unique Guide consists of over 170 hand-selected references published in peer-reviewed journals with links to the article abstracts and full-text sources. The Guide captures the entire spectrum of clinical and scientific knowledge about adjacent segment disc disease that has been accumulated over the past decade.

Adjacent Segment Disc Disease is a one-of-a-kind literature reference Guide that includes:

  • A comprehensive bibliography of 175 journal article references indexed in MEDLINE published in well respected medical and scientific journals.
  • Online access to the abstracts (summaries) of the articles.
  • Online access to the free full-text version of 31 articles.
  • Links to full-text sources of other articles that are available for purchase directly from individual journal publishers.
  • A unique “Author Directory” consisting of the names and institutional affiliations of experts who have published and have specialized knowledge about Adjacent Segment Disc Disease. The “Author Directory” is a valuable resource for quickly identifying and locating experts for case reviews, opinions, and testimony.

Select examples of topics that are covered by the articles referenced in this Guidebook include:

  • Adjacent segment disease after posterior lumbar interbody fusion (PLIF).
  • Reoperation for adjacent segment disease after anterior cervical fusion.
  • Risk factors for predicting symptomatic adjacent segment disease requiring surgery in patients after posterior lumbar fusion.
  • The revision rate and occurrence of adjacent segment disease after anterior cervical discectomy and fusion.
  • Comparison of adjacent segment disease after minimally invasive or open lumber interbody fusion.
  • Update on the evidence for adjacent segment degeneration and disease.
  • Systematic review and meta-analysis of the prevalence of adjacent segment disease after spine surgery.
  • Symptomatic adjacent segment disease after cervical total disc replacement.
  • Pain, disability, and quality of life in patients with adjacent segment disease treated with laminectomy and extension of instrumented fusion.
  • Predicting the risk of adjacent segment disease after surgery of the cervical and lumbar spine.
The MediFocus Literature Guide on Adjacent Segment Disc Disease
is available in two formats:

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